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People

P.I.: Rovshan G. Sadygov, PhD
email: rgsadygo@utmb.edu

Lab members:

Henock M. Deberneh, Ph.D.
1) Deberneh HM. , Abdelrahman DR, Verna SK, Linares JJ, Murton AJ, Russell WK, Kuyumcu-Martinez MN, Miller BF, Sadygov RG. Quantifying Label enrichment from two mass isotopomers increases proteome coverage for in vivo protein turnover using heavy water metabolic labeling. Communications Chemistry, 2023, 6 (1):72.
2) Deberneh HM , Taylor ME, Borowik AK, Miyagi M, Miller BF, and Sadygov RG, Numbers of Exchangeable Hydrogens from LC–MS Data of Heavy Water Metabolically Labeled Samples, J. Am. Soc. Mass Spectrom. 2024, 35, 1826−1837.

Justin X. Zhu, B.S.
Sadygov RG, Zhu JX, Deberneh HM, Exact Integral Formulas for False Discovery Rate and the Variance of False Discovery Proportion, J. Proteome Res. 2024, 23, 2298−2305.

Former members:
Ahmad Borzou, Ph.D., awarded NLM Training Grant in Biomedical Informatics , 1/1/19 → 12/31/20
1) Borzou A. and Sadygov RG, A Novel Estimator of the Interaction Matrix in Graphical Gaussian Model of Omics Data Using the Entropy of Non-Equilibrium Systems. Bioinformatics, 2021; 37(6):837-44.
2) Borzou A. , Yousefi R., and Sadygov RG, Another Look at Matrix Correlations, Bioinformatics, 35(22), 2019, 4748–4753.

Alexey Nefedov, Ph.D.
Nefedov AV, Mitra I, Brasier AR, Sadygov RG, Examining Troughs in the Mass Distribution of All Theoretically Possible Tryptic Peptides, Journal of Proteome Research 2011;10:4150.

Jayant Avva, Ph.D.
Sadygov RG, Avva J, Rahman M, Lee K, Sergei Ilchenko S, Kasumov T., and Borzou A., d2ome, Software for in Vivo Protein Turnover Analysis Using Heavy Water Labeling and LC–MS, Reveals Alterations of Hepatic Proteome Dynamics in a Mouse Model of NAFLD, Journal of Proteome Research, 2018 17(11):3740-3748

Poonam Desai, M.S.
Desai P., Yang J., Tian B., Sun H., Kalita M., Ju H., Paulucci-Holthauzen A., Zhao Y., Brasier A.R., and Sadygov RG; Mixed-Effects Model of Epithelial-Mesenchymal Transition Reveals Rewiring of Signaling Networks. Cellular Signalling, 2015;27:1413–1425.

Miroslaw J Gilski, Ph.D.
Gilski M. J., Sadygov RG, Comparison of Programmatic Approaches for Efficient Accessing to mzML Files, Data Mining in Genomics and Proteomics 2011;2:109.

Matthew C. Leitch, M.S.
Leitch MC, Mitra I., Sadygov RG, Generalized Linear and Mixed Models for Label-Free Shotgun Proteomics, Statistics and Its Interface, 2012;5(1):89-98

Indranil Mitra, Ph.D.
Mitra I., Nefedov AV, Brasier A. R., Sadygov RG, Improved mass defect model for theoretical tryptic peptides, Analytical Chemistry, 2012;84(6):3026-32.

Mahbubur Rahman, Ph.D.
Rahman M, Sadygov RG, Predicting the protein half-life in tissue from its cellular properties, PLoS ONE 2017 12(7):e0180428. doi: 10.1371/journal.pone.0180428